mibelle group perusahaan yang menaungi Phytocelltec memenangi best cosmetic business award 2013

Buchs, July 2013

Cosmetics Business Award 2013 Winner

The research and development company Mibelle Biochemistry, which belongs to the Mibelle Group, wins the "2013 cosmetics business award" in the "Innovation in Ingredients" category with its PhytocellTecTM Symphytum. This active ingredient activates the skin stem cells in the epidermis and thus accelerates the renewal of the skin. Mibelle Biochemistry develops and produces active ingredients that are sold to companies in the cosmetic sector around the world. With the new ingredient based on plant stem cells, the natural scientists have now notched up yet another success.

PhytoCellTecTM – the ground-breaking anti-ageing ingredient technology on the basis of plant stem cells

With PhytoCellTecTM Malus Domestica, Mibelle Biochemistry launched an entirely new active ingredient on the basis of plant stem cells of the Uttwiler Spätlauber apple. This apple has now acquired an almost legendary reputation. Entirely in accordance with the motto "inspired by nature realized by science", Mibelle has thus created a basis for combining nature and science so that new plant-based raw materials can be used in cosmetics and offer revolutionary results. PhytoCellTecTM Malus Domestica was the first cosmetic raw material worldwide on the basis of plant stem cells. It generated global interest and enthusiasm as soon as it was launched. The new active ingredient from apples was seen as ground-breaking because the vitality and efficiency of the most important skin cells, i.e. the skin stem cells, could be demonstrably improved for the first time with the use of plant stem cells. Mibelle Biochemistry won the European Cosmetics Innovation Prize for it at the 2008 in-cosmetics.

New milestone with PhytoCellTecTM Symphytum

PhytoCellTec™ Symphytum is an active ingredient that is based on stem cells of the comfrey root (symphytum officinale). It activates the skin stem cells in the epidermis and thus accelerates the regeneration of the skin. Symphytum officinale has been used as a medicinal plant for centuries. The name "symphytum" comes from the Greek word "sympho" ("to unite") and "phyton" ("plant"). In Ancient Greece, doctors used symphytum on bone fractures and to aid the healing of wounds. There is still widespread use of comfrey extracts today to treat wounds, bruises, strains and sprains.

Epidermal stem cells and their function

Epidermal stem cells are located in the lowest cell layer of the epidermis. They are continually dividing and are differentiated into skin tissue cells, whilst old cells are shed on the skin's surface. This constant renewal is important for the quality of the skin's barrier and ensures that the skin remains smooth and even. As we grow older, this renewal process slows discernibly as the skin stem cells also age and thus their ability to divide declines. The result is a thinner, dry and rough skin with a pale complexion.

With PhytoCellTec™ Symphytum, the skin stem cells are protected and activated at the same time. The skin regeneration is thus accelerated and the skin can regenerate better and more quickly. The result is a visibly smoother and radiant skin. The active ingredient increases the natural ability of the skin stem cells to reduce and repair the visible signs of ageing.

http://www.mibellegroup.com/en/news/cosmeticsbusinessaward

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A Swiss apple a day keeps wrinkles at bay

November 28, 2009 - 10:08

A rare Swiss apple is being hailed in the cosmetic and fashion world as an exciting anti-ageing breakthrough – even Michelle Obama is rumoured to be a fan.

Used in creams and serums, stem cells from the Uttwiler Spätlauber apple are said to protect skin cell regeneration and so delay the onset of wrinkles. The discovery was made by a Swiss company.

The November edition of the United States Vogue magazine went as far as to call the variety "the super-apple", and asked if the tree could be "the new fountain of youth".

The Uttwiler Spätlauber, which was first recorded in the 18th century, comes from canton Thurgau, in northern Switzerland.

It is well known for its excellent storability; it can stay fresh looking for up to four months after being harvested, long after other varieties have become wrinkled.

However, it has not been widely cultivated of late because of its sour taste and the number of trees have dwindled.

Amazing longevity

Having collected some samples, Swiss researchers set to work and found that the answer mostly lay in the amazing longevity of the apple's stem cells.

Humans have skin stem cells, which replenish and maintain the balance of cells within the skin tissue and regenerate tissue which has been damaged.

But with age, the number of skin stem cells decreases and their ability to repair the skin becomes less efficient. The result is – with added environmental damage like UV rays - a loss of skin vitality, and inevitably, wrinkles.

Mibelle Biochemistry, which developed the apple ingredient, found that the apple stem cells were protecting the skin stem cells from ageing.

"We thought there must be something in those apples which give them their long shelf life," said Beata Hurst, marketing and sales manager at Mibelle Biochemistry.

"We could show that the apple stem cells have a positive influence on the vitality of the skin stem cells, they made them more efficient and they can live longer," Hurst told swissinfo.ch.

The firm, which is a subsidiary of the big Swiss retailer Migros, used a novel technology to replicate the apple cells called PhytoCellTec™.

Michelle Obama

The apple ingredient has been snapped up by cosmetics companies in Europe, Asia, and the United States, including Lancôme and Chantecaille.

According to the Vogue article, style icon and presidential wife Michelle Obama buys a serum using the apple made by Clark's Botanicals, costing $355 (SFr361).

The Uttwiller Spätlauber was found in one of the collections belonging to ProSpecieRara, a foundation aiming to preserve traditional breeds of animals and plants in Switzerland.

ProSpecieRara director Béla Bartha told swissinfo.ch that there were only 20 Uttwiller Spätlauber trees left at present, which he said was not surprising. Some fruit varieties have between one and five trees left.

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jennifer lopez juga pakai apple stem cell dr swiss

15ml Pure Swiss Apple Stem Cell Anti-Aging Extract (PhytoCellTec™ Malus Domestica) – Commercial Grade for use in DIY recipes and adding to your favorite beauty products.

Vogue has dubbed it "the super apple" and asked if the tree could be "the new fountain of youth". The variety was first recorded in the mid-18th century, found only in northern Switzerland. If the tree's bark or the skin of an unpicked fruit is punctured it heals.  Once picked, an Uttwiler Spätlauber (Swiss Apple) lasts months longer than any other apple in the world.

Swiss scientists at Mibelle Biochemistry found the key to the apple's longevity lay chiefly in its unusually resilient stem cells. In clinical tests the apple's stem cells appeared to be protecting human stem cells. They nourished and stimulated cells while defending them against UV radiation. In one study, the scientists made a cream containing two per cent Uttwiler Spätlauber extract and applied it twice daily to the "crow's feet" under the eyes of 20 participants. Wrinkle depth was reduced by an average of 15% after four weeks. Other studies have demonstrated its age delaying and anti-wrinkle effects.

Gwenyth Paltro, Jennifer Lopez and Michele Obama first made Swiss Apple stem cells famous after admitting they use products costing hundreds of dollars an ounce. But you don’t have to spend hundreds of dollars because you can add pure Swiss Apple extract to your favorite beauty products for pennies.

This semi-liquid gel can easily be mixed into a variety of lotions, creams, cleansers, etc… Suggested use is 2% of the overall volume. For instance, a 4 ounce jar of cream would only require (2.5 ml) of extract. You can use a non-needle syringe available at any drugstore to add the desired amount. Simply mix with small whisk or whatever works. Just make sure you rinse any utensil with rubbing alcohol and dry thoroughly before stirring the cream or serum.

Ingredients: Malus Domestica Fruit Cell Culture Extract (and) Xanthan Gum (and) Glycerin (and) Lecithin (and) Phenoxyethanol (and) Water.

Product Fill Weight: 15ml / 0.5 fl oz

sumber : http://www.greensations.com/PhytoCellTec-Swiss-Apple-Stem-Cell-Extract-p/swissapple.htm

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Swiss apple is key to Michelle Obama's youthful looks

According to the US edition of Vogue, the First Lady buys a £215 serum which uses an extract from the stem cells of the Uttwiler Spätlauber apple.

The variety stays fresh for up to four months after being harvested, long after other varieties have become wrinkled.

Used in creams and serums, stem cells from the fruit are said to stimulate human skin stem cells, thereby protecting skin cell regeneration and delaying the onset of wrinkles.

It is being hailed in the cosmetic world as an exciting anti-ageing breakthrough and has been snapped up by around 100 beauty firms in Europe, Asia, and the United States, including Lancôme and Chantecaille.

Vogue has dubbed it "the super apple" and asked if the tree could be "the new fountain of youth".

Despite its long shelf-life, the apple has not been considered desirable until now because of its tart taste. Consequently the number of trees has rapidly dwindled.

The variety, first recorded in the mid-18th century, comes from northern Switzerland. If the tree's bark or the skin of an unpicked fruit is punctured it heals. And once picked, an Uttwiler Spätlauber apple lasts months longer than its shrivelled cousins.

Swiss scientists at Mibelle Biochemistry, which is a subsidiary of the big Swiss retailer Migros, decided to investigate whether the miracle component could be harnessed to stop the ageing process in people.

They found the key to the apple's longevity lay chiefly in its unusually resilient stem cells.

In clinical tests the apple's stem cells appeared to be protecting human stem cells. They nourished and stimulated them and defended them against UV radiation.

They made a cream containing a two per cent Uttwiler Spätlauber extract and applied it twice daily to the "crow's feet" area under the eyes of 20 participants. Wrinkle depth was reduced by an average of 15 per cent after four weeks.

"We thought there must be something in those apples which gives them their long shelf life," said Beata Hurst, marketing and sales manager at Mibelle Biochemistry.

"We could show that the apple stem cells have a positive influence on the vitality of the skin stem cells. They made them more efficient and they can live longer."

At present there are only 20 Uttwiller Spätlauber trees in Switzerland. They belong to ProSpecieRara, a foundation aiming to preserve traditional breeds of animals and plants in Switzerland.

The organisation has managed to preserve 1,800 varieties on 8,000 trees during its 25 years in operation, through collecting samples, growing them and then distributing them to people willing to look after them.

Bela Bartha, foundation director, said: "We have undiscovered treasures in these collections."

sumber : http://www.telegraph.co.uk/news/worldnews/michelle-obama/6684364/Swiss-apple-is-key-to-Michelle-Obamas-youthful-looks.html

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pentingnya perawatan "antiaging" sejak dini

Perempuan Perancis Tampak 7 Tahun Lebih Muda Inilah Rahasia Kecantikannya. Jangan kelewat percaya diri jika saat ini Anda dibilang punya baby face, karena saat keriput akhirnya menghias wajah, Anda pasti akan berbalik sangat tidak percaya diri. Dan, akan terlambat jika Anda baru akan memakai krim antipenuaan di usia 40 tahun.

Mumpung Anda belum berusia 40 tahun, coba contoh kebiasaan perempuan Perancis. Lebih dari 80 persen perempuan Inggris berusia 40 tahun menilai bahwa perempuan Perancis di usia yang sama terlihat tujuh tahun lebih muda, demikian menurut penelitian dari Escentual.com.

Survei tersebut juga menunjukkan, kebanyakan perempuan Inggris mengatakan bahwa rahasia awet muda perempuan Perancis adalah rutinitas mereka dalam menggunakan produk antipenuaan dini. Mereka diketahui mulai menggunakan produk krim antiaging, serum, dan skin repair, lima tahun lebih awal daripada perempuan Inggris.

Sebanyak 33 persen perempuan Perancis mulai memakai produk-produk antipenuaan pada usia 15 tahun. Pada usia 20 tahun, hampir dua per tiga perempuan Perancis sudah menggunakan merek-merek farmasi Perancis yang berspesialisasi dalam antipenuaan, seperti Avene, La Roche-Posay, dan Caudalie.

Di lain pihak, perempuan Inggris baru memulai rutinitas perawatan kulitnya pada usia 25, bahkan hanya separuh perempuan Inggris yang akan mengaplikasikan perawatan antiaging secara teratur.

“Perempuan Inggris cenderung mulai menggunakan produk-produk antiaging ketika mereka mulai melihat efek pertama dari penuaan, yang bisa saja sedikit terlambat. Sedangkan perempuan Perancis seringkali mengambil langkah pencegahan dengan mulai memakainya di akhir usia belasan,” kata pakar perawatan kulit Escentual.com, Emma Leslie.

Merek-merek farmasi Perancis seperti disebut tadi tergolong “pemimpin” dalam industri kecantikan, khususnya perawatan antipenuaan. Negara ini menjadi pengguna produk antiaging terbesar di Eropa, dengan menghabiskan 1,9 milyar poundsterling (sekitar Rp 28 trilyun/tahun 2009) untuk perawatan wajah. Rata-rata perempuan Perancis berusia di atas 15 tahun menghabiskan dana 78 poundsterling (sekitar Rp 1,1 juta) setahun untuk membeli produk-produk ini.

Kini, perempuan Inggris pun berharap merek-merek tersebut masuk ke Inggris sehingga mereka bisa meniru resep kecantikan perempuan Perancis.

Sumber: Female First, kompas.com

http://www.kecantikan.web.id/tips-cantik/perempuan-perancis-tampak-7-tahun-lebih-muda-inilah-rahasia-kecantikannya.htm

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Rio+20: Fred Zuelli, Mibelle

dr Fred zulli founter dari phytocelltec mempresentasikan bagaimana apple uttwiller spatlauber (malus domestica) di budidayakan dan di kembangbiakna dalam sebuah bio reactor.



apel-apel tersebut di kembangbiakan dengan cara di kultur dan teknologi bioreactor yang beliau ciptakan sebagai titik kontrol kualitas dari apel-apel tersebut.

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MARKETING PLAN

MARKETING PLAN

Untuk bergabung dengan biogreen science  ada 3 macam paket:
1.Silver Package = $110 mendapatkan 1 box apple stem cells elastic collagen (isi 30 sachet untuk pemakaian 30 hari)
2. Gold package = $550 mendapatkan 5 box apple stem cells elastic collagen (untuk pemakaian 5 bulan)
3. Platinum Package = $1100 mendapatkan 10 box apple stem cells elastic collagen (untuk pemakaian 10 bulan).khusus untuk platinum package mendapatkan bonus 5% dari registrasi member

kurs Jual =$1 = Rp 12000
kurs beli =$1 = Rp 10000


BONUS SPONSOR

Silver member

Silver member maksimum perhari 24 pair atau max $5940/bulan
Gold Member

gold member maksimum perhari 200 pair atau max $37.800/bulan

Platinum member

Khusus platinum member unlimited pair dan unlimited bonus perbulan

monthly income

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apa itu stem cell

Biogreen science MEMPERKENALKAN product unggulan yang berasal dari negara  Switzerland dengan "kandungan inti" stem cells apple Uttweiler spatlauber dan collagen dari ekstrak telur ikan salmon dan sari sarang burung walet.

apa itu stem cells??

Stem Cell adalah sel induk yang berfungsi untuk membentuk sel baru.

stem cells (sel induk) memiliki sifat2 :

1. pembaharuan(self-renewal) : bisa melewati beberapa siklus pembelahan untuk mempertahankan jumlahnya.

2. diferensiasi : kapasitas untuk berubah menjadi sel spesifik untuk memperbaiki dan mengganti sel yang rusak dan membangun jaringan yang baru .

ADA 2 JENIS STEM CELL

Embryonic Stem Cell adalah sel induk (sel punca) yang merupakan cikal bakal atau sel mula-mula yang berkembang biak membentuk seluruh organ tubuh makhluk hidup (pluripoten). Stem Cell inilah yang terus menerus membelah diri sehingga terbentuk janin yang kemudian lahir sebagai bayi

Adult Stem Cell adalah sel induk yang sudah dewasa, artinya sudah memiliki fungsi spesifik dan hanya mampu membentuk beberapa jenis sel yang segolongan saja (multipoten), misalnya Stem Cell Jantung  hanya dapat membentuk sel otot jantung, sel otot polos dan endotel. Therapy menggunakan Adult Stem Cell sudah digunakan selama puluhan tahun, namun Karena biayanya yang sangat mahal dan prosedur yang sangat rumit, tidak banyak pasien yang berkesempatan menjalani therapy ini.

kenapa dengan mengkonsumsi biogreen apple stem cells bisa berpengaruh kepada kulit manusia ??

1.sel induk pada kulit terdapat di basal layer, yang berfungsi untuk menggantikan sel pada saat deskuamasi(penggantian kulit baru)

2. ketika sel induk tidak berfungsi lagi, terjadi pengurangan jumlah sel yang mengakibatkan kulit menjadi kasar dan keriput

3. pada proses penuaan, sel induk kulit tidak lagi mampu membelah diri untuk  mengganti kulit yang baru, terjadilah problem kosmetik.

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